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Hexb-T2A-CreERT2
製品ID :
C001580
系統:
C57BL/6JCya
状況:
説明:
The Hexb-T2A-CreERT2 mouse was constructed by integrating the T2A-CreERT2 gene expression cassette into the mouse Hexb gene using gene-editing technology, allowing for the expression of CreERT2 recombinase under the control of the mouse Hexb gene regulatory elements. In the absence of tamoxifen treatment, CreERT2 recombinase is primarily located in the cytoplasm. Only under the action of tamoxifen can CreERT2 recombinase enter the nucleus and exert its recombination function. When Hexb-T2A-CreERT2 mice are crossed with mice containing loxP sites, tamoxifen induction is expected to trigger Cre recombinase-mediated sequence recombination between loxP sites in the nervous system (microglia) of the offspring.
The Hexb-T2A-CreERT2 mouse was constructed by integrating the T2A-CreERT2 gene expression cassette into the mouse Hexb gene using gene-editing technology, allowing for the expression of CreERT2 recombinase under the control of the mouse Hexb gene regulatory elements. In the absence of tamoxifen treatment, CreERT2 recombinase is primarily located in the cytoplasm. Only under the action of tamoxifen can CreERT2 recombinase enter the nucleus and exert its recombination function. When Hexb-T2A-CreERT2 mice are crossed with mice containing loxP sites, tamoxifen induction is expected to trigger Cre recombinase-mediated sequence recombination between loxP sites in the nervous system (microglia) of the offspring.
Lancl2-flox
製品ID :
S-CKO-15212
系統:
C57BL/6JCya
状況:
説明:
Lancl2 is located on chromosome 6 of mice. SgRNA and ssDNA were designed using Nuclease Technology; Lancl2 conditional knockout mice were obtained by high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
Lancl2 is located on chromosome 6 of mice. SgRNA and ssDNA were designed using Nuclease Technology; Lancl2 conditional knockout mice were obtained by high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
Hexb-KO
製品ID :
S-KO-20715
系統:
C57BL/6JCya
状況:
説明:
Hexb is located on chromosome 13 of mice. Nuclease Technology was used to design sgRNA; Hexb knockout mice were obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
Hexb is located on chromosome 13 of mice. Nuclease Technology was used to design sgRNA; Hexb knockout mice were obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
Hexb-flox
製品ID :
S-CKO-20117
系統:
C57BL/6JCya
状況:
説明:
Hexb is located on chromosome 13 of mice. SgRNA and ssDNA will be designed using Nuclease Technology; Hexb conditional knockout mice will be obtained by high-throughput electroporation of fertilized eggs. After sexual maturity, sperm will be collected for cryopreservation.
Hexb is located on chromosome 13 of mice. SgRNA and ssDNA will be designed using Nuclease Technology; Hexb conditional knockout mice will be obtained by high-throughput electroporation of fertilized eggs. After sexual maturity, sperm will be collected for cryopreservation.
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