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Zbtb46-IRES-iCre
製品ID :
C001574
系統:
C57BL/6JCya
状況:
説明:
The Zbtb46-IRES-iCre mouse was constructed by integrating the IRES-iCre expression cassette downstream of the TAG stop codon in the endogenous mouse Zbtb46 gene. The expression pattern of the iCre recombinase (codon-optimized Cre recombinase) is similar to that of the mouse Zbtb46 gene. When Zbtb46-IRES-iCre mice are crossed with mice containing loxP sites, the offspring are expected to exhibit Cre recombinase-mediated sequence recombination between loxP sites in the immune system (conventional dendritic cells, cDC).
The Zbtb46-IRES-iCre mouse was constructed by integrating the IRES-iCre expression cassette downstream of the TAG stop codon in the endogenous mouse Zbtb46 gene. The expression pattern of the iCre recombinase (codon-optimized Cre recombinase) is similar to that of the mouse Zbtb46 gene. When Zbtb46-IRES-iCre mice are crossed with mice containing loxP sites, the offspring are expected to exhibit Cre recombinase-mediated sequence recombination between loxP sites in the immune system (conventional dendritic cells, cDC).
Zbtb46-P2A-CreERT2
製品ID :
C001575
系統:
C57BL/6JCya
状況:
説明:
The Zbtb46-P2A-CreERT2 mouse was constructed by integrating the P2A-CreERT2-WPRE-BGH pA gene expression cassette into the mouse Zbtb46 gene using gene-editing technology, allowing for the expression of CreERT2 recombinase under the control of the mouse Zbtb46 gene regulatory elements. In the absence of tamoxifen treatment, CreERT2 recombinase is primarily located in the cytoplasm. Only under the action of tamoxifen can CreERT2 recombinase enter the nucleus and exert its recombination function. When Zbtb46-P2A-CreERT2 mice are crossed with mice containing loxP sites, tamoxifen induction is expected to trigger Cre recombinase-mediated sequence recombination between loxP sites in the immune system (conventional dendritic cells, cDC) of the offspring.
The Zbtb46-P2A-CreERT2 mouse was constructed by integrating the P2A-CreERT2-WPRE-BGH pA gene expression cassette into the mouse Zbtb46 gene using gene-editing technology, allowing for the expression of CreERT2 recombinase under the control of the mouse Zbtb46 gene regulatory elements. In the absence of tamoxifen treatment, CreERT2 recombinase is primarily located in the cytoplasm. Only under the action of tamoxifen can CreERT2 recombinase enter the nucleus and exert its recombination function. When Zbtb46-P2A-CreERT2 mice are crossed with mice containing loxP sites, tamoxifen induction is expected to trigger Cre recombinase-mediated sequence recombination between loxP sites in the immune system (conventional dendritic cells, cDC) of the offspring.
Zbtb46-KO
製品ID :
S-KO-20354
系統:
C57BL/6JCya
状況:
説明:
Zbtb46 is located on chromosome 2 of mice. Nuclease Technology was used to design sgRNA; Zbtb46 knockout mice were obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
Zbtb46 is located on chromosome 2 of mice. Nuclease Technology was used to design sgRNA; Zbtb46 knockout mice were obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
Zbtb46-flox
製品ID :
S-CKO-15374
系統:
C57BL/6JCya
状況:
説明:
Zbtb46 is located on chromosome 2 of mice. SgRNA and ssDNA were designed using Nuclease Technology; Zbtb46 conditional knockout mice were obtained by high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
Zbtb46 is located on chromosome 2 of mice. SgRNA and ssDNA were designed using Nuclease Technology; Zbtb46 conditional knockout mice were obtained by high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
Zbtb46-KO
製品ID :
S-KO-13849
系統:
C57BL/6JCya
状況:
説明:
Zbtb46 is located on chromosome 2 of mice. Nuclease Technology will be used to design sgRNA; Zbtb46 knockout mice will be obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
Zbtb46 is located on chromosome 2 of mice. Nuclease Technology will be used to design sgRNA; Zbtb46 knockout mice will be obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
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